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Vitamin EIn studies, Vitamin E has been shown to help prevent arteries from clogging by blocking the conversion of cholesterol into the waxy fat deposits called plaque that stick to blood vessel walls. Also, importantly from anti aging perspective, it has been noted in research that people with cancer often have lower levels of vitamin E. In laboratory studies, the compound has inhibited the growth of some cancers in test tubes and animals, particularly hormone responsive cancers such as breast and prostate. However, the research on the compound and its cancer preventing abilities still need very much research. The same goes for some preliminary signs that vitamin E may have preventitive properties to Alzheimer's disease. Vitamin E - StudiesAberg F, Appelkvist EL, Broijersen A, et al. Gemfibrozil-induced decrease in serum ubiquinone and alpha- and gamma-tocopherol levels in men with combined hyperlipidaemia. Eur J Clin Invest. 1998;28(3):2352-2342. Adhirai M, Selvam R. Effect of cyclosporin on liver antioxidants and the protective role of vitamin E in hyperoxaluria in rats. J Pharm Pharmacol. 1998;50(5):501-505. Albanes D, Malila N, Taylor PR, et al. Effects of supplemental alpha-tocopherol and beta-carotene on colorectal cancer: results from a controlled trial (Finland). Cancer Causes Control. 2000;11:197-205. Allard JP, Aghdassi E, Chau J, et al. Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects. AIDS. 1998;13:1653-1659. Altura BM, Gebrewold A. Alpha-tocopherol attenuates alcohol-induced cerebral vascular damage in rats: possible role of oxidants in alcohol brain pathology and stroke. Neurosci Lett. 1996;220(3):207-210. Ames BN. Micronutrient deficiencies: A major cause of DNA damage. Ann NY Acad Sci. 2000;889:87-106. Anderson JW, Gowri MS, Turner J,et al. Antioxidant supplementation effects low density lipoprotein oxidation for individuals with type 2 diabetes mellitus. J Amer Coll Nutr. 1999;18:451-461. Babu JR, Sundravel S, Arumugam G, Renuka R, Deepa N, Sachdanandam P. Salubrious effect of vitamin C and vitamin E on tamoxifen-treated women in breast cancer with reference to plasma lipid and lipoprotein levels. Cancer Lett. 2002;151:1-5. Belda JI, Roma J, Vilela C, Puertas FJ, Diaz-Llopis M, Bosch-Morell F, Romero FJ. Serum vitamin E levels negatively correlate with severity of age-related macular degeneration. Mech Ageing Dev. 1999;107(2):159-164. Bhaumik G, Srivastava KK, Selvamurthy W, Purkayastha SS. The role of free radicals in cold injuries. Int J Biometeorol. 1995;38(4):171-175. Bursell S, Clermont AC, Aiello LP, et al. High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes. Diabetes Care. 1999;22(8):1245-1251. Cai J, Nelson KC, Wu M, Sternberg P Jr, Jones DP. Oxidative damage and protection of the RPE. Prog Retin Eye Res. 2000;19(2):205-221. Chang T, Benet LZ, Hebert MF. The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers. Clin Pharm & Ther. 1996;59(3):297-303. Christen WG, Ajani UA, Glynn RJ, Manson JE, Schaumberg DA, Chew EC, Buring JE, Hennekens CH. Prospective cohort study of antioxidant vitamin supplement use and the risk of age-related maculopathy. Am J Epidemiol. 1999;149(5):476-484. Ciavatti M, Renaud S. Oxidative status and oral contraceptive. Its relevance to platelet abnormalities and cardiovasular risk. Free Radic Biol Med. 1991;10(5)L325-338. Clemente C, Caruso MG, Berloco P, Buonsante A, Giannandrea B, Di Leo A. Alpha-tocopherol and beta-carotene serum levels in post-menopausal women treated with transdermal estradiol and oral medroxyprogesterone acetate. Horm Metab Res. 1996;28(10):558-561. Collaborative Group of the Primary Prevention Project. Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Lancet. 2001;357:89-95. Corrigan JJ. 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Gaby AR. Natural treatments for osteoarthritis. Altern Med Rev. 1999;4(5):330-341. GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet. 1999;354:447-455. Gogu S, Beckman B, Rangan S, et al. Increased therapeutic efficacy of zidovudine in combination with vitamin E. Biochem Biophys Res Commun. 1989; 165:401-407. Greenberg ER, Baron JA, Tosteson TD, et al. A clinical trial of antioxidant vitamins to prevent colorectal adenoma. N Engl J Med. 1994;331:141-147. Heart Outcomes Prevention Evaluation Study Investigators. Vitamin E supplementation and cardiovascular events in high-risk patients. N Engl J Med. 2000;342:154-160. Helzlsouer KJ, Huang HY, Alberg AJ, et al. Association between alpha-tocopherol, gamma-tocopherol, selenium and subsequent prostate cancer. J Natl Cancer Inst. 2000 Dec 20;92(24):2018-2023. Hodis HN, Mack WJ, LaBree L et al. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. JAMA. 1995;273(23):1849-1854. Inal M, Sunal E, Kanbak G, Zeytinoglu S. Effects of postmenopausal hormone replacement therapy and alpha-tocopherol on the lipid profiles and antioxidant status. Clin Chim Acta. 1997;268(1-2):21-29. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. 2000; National Academy Press. Jacques PF. The potential preventive effects of vitamins for cataract and age-related macular degeneration. Int J Vitam Nutr Res. 1999;69(3):198-205. Jänne PA, Mayer RJ. Chemoprevention of colorectal cancer. N Engl J Med. 2000;342(26):1960-1968. Kim JM, White RH. Effect of vitamin E on the anticoagulant response to warfarin. Am J Cardiol. 1996;77(7):545-546. Kimmick GG, Bell RA, Bostick RM. Vitamin E and breast cancer: a review. Nutr Cancer. 1997;27(2):109-117. Kitiyakara C, Wilcox C. 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