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Vitamin B5The vitamin is one of eight water-soluble B vitamins, all of which help the body to convert carbohydrates into glucose, for energy for the body to use. B complex vitamins also play an important role in maintaining muscle tone in the gastrointestinal tract and promoting the health of the nervous system, skin, hair, eyes, mouth, and liver. From anti aging perspective, B5 vitamin is particularly important for its ability to assist in maintaining a healthy digestive tract and it helps the body use other vitamins (particularly vitamin B2) more effectively. Also, this vitamin also enhances the activity of the immune system and improves the body's ability to withstand stressful conditions. Vitamin B5 also fights aging because it is a constituent of coenzyme A, which is involved in many chemical reactions essential to life, including detoxification of dangerous substances. From skin anti aging perspective, of particular interest has been of late a clinical study performed by Dr. Lit-Hung Leung in Singapore, in which vitamin B5 was effectively used for acne treatment. (Pantothenic Acid in the Treatment of Acne Vulgaris “A Medical Hypothesis” by Lit-Hung Leung, M.D. Journal of Orthromolecular Medicine Vol. 12 Number 2, 1997.) Taking any one of the B complex vitamins for a long period of time can result in an imbalance of other important B vitamins. For this reason, it is generally important to take a B complex vitamin with any single B vitamin. Vitamin B5 - StudiesAdding vitamins to the mix: skin care products that can benefit the skin [press release]. American Academy of Dermatology; March 11, 2000. Antoon AY, Donovan DK. Burn Injuries. In: Behrman RE, Kliegman RM, Jenson HB, eds. Nelson Textbook of Pediatrics. Philadelphia, Pa: W.B. Saunders Company; 2000:287-294. Aprahamian M, Dentinger A, Stock-Damge C, Kouassi JC, Grenier JF. Effects of supplemental pantothenic acid on wound healing: experimental study in rabbit. Am J Clin Nutr. 1985;41(3):578-89. Arsenio L, Bodria P, Magnati G, Strata A, Trovato R.. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clin Ther. 1986;8:537–545. Bertolini S, Donati C, Elicio N, et al. Lipoprotein changes induced by pantethine in hyperlipoproteinemic patients: adults and children. Int J Clin Pharmacol Ther Toxicol. 1986;24:630–637. Coronel F, Tornero F, Torrente J, et al. Treatment of hyperlipemia in diabetic patients on dialysis with a physiological substance. Am J Nephrol. 1991;11:32–36. De-Souza DA, Greene LJ. Pharmacological nutrition after burn injury. J Nutr. 1998;128:797-803. Gaddi A, Descovich GC, Noseda G, et al. Controlled evaluation of pantethine, a natural hypolipidemic compound in patients with different forms of hyperlipoproteinemia. Atherosclerosis. 1984;50:73–83. General Practitioner Research Group. Calcium pantothenate in arthritic conditions. A report from the General Practitioner Research Group. Practitioner. 1980;224(1340):208-211 Hoeg JM. Pharmacologic and surgical treatment of dyslipidemic children and adolescents. Ann NY Acad Sci. 1991;623:275-284. Kelly GS. Nutritional and botanical interventions to assist with the adaptation to stress. [Review]. Altern Med Rev. 1999 Aug;4(4):249-265. Kirschmann GJ, Kirschmann JD. Nutrition Almanac. 4th ed. New York: McGraw-Hill;1996:115-118. Lacroix B, Didier E, Grenier JF. Role of pantothenic and ascorbic acid in wound healing processes: in vitro study on fibroblasts. Int J Vitam Nutr Res. 1988;58(4):407-413. McCarty MF. Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine. Med Hypotheses. 2001;56(3):314-317. Meyer NA, Muller MJ, Herndon DN. Nutrient support of the healing wound. New Horizons. 1994;2(2):202-214. Naruta E, Buko V. Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose. Exp Toxicol Pathol. 2001;53(5):393-398. Nutrients and Nutritional Agents. In: Kastrup EK, Hines Burnham T, Short RM, et al, eds. Drug Facts and Comparisons. St. Louis, Mo: Facts and Comparisons; 2000:4-5. Pizzorno JE, Murray MT. Textbook of Natural Medicine. Vol 1. 2nd ed. Edinburgh: Churchill Livingstone; 1999. Weimann BI, Hermann D. Studies on wound healing: effects of calcium D-pantothenate on the migration, proliferation and protein synthesis of human dermal fibroblasts in culture. Int J Vitam Nutr Res. 1999;69(2):113-119. White-O'Connor B, Sobal J. Nutrient intake and obesity in a multidisciplinary assessment of osteoarthritis. Clin Ther. 1986;9 Suppl B:30-42.
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