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TocotrienolsThese compounds exist in four different forms or isomers, named alpha-, beta-, gamma- and delta- tocotrienol. What makes these compounds exciting from antiaging perspective, is that all the isomers are important antioxidants (due to the ease of donating a hydrogen atom from the hydroxyl group on the chromanol ring to reduce free radicals), each of them also has its own biological activity apart from the group profile. In comparison to tocopherols, tocotrienols have shown in research considerably superior antioxidant properties compared to dl-á-Tocopherol in clinical and experimental studies due to their better distribution in the fatty layers of the cell membrane. In addition, the antioxidant function of tocotrienols is also associated with lowering tumor formation, DNA damage and cell damage. Tocotrienols - StudiesKhanna S, Roy S, Slivka A, Craft T, Chaki S, Rink C, Notestine M, DeVries A, Parinandi N, Sen C (2005). "Neuroprotective properties of the natural vitamin E alpha-tocotrienol". Stroke 36 (10): 2258-64. Nesaretnam K, Ambra R, Selvaduray KR, et al. (2004). Tocotrienol-rich fraction from palm oil and gene expression in human breast cancer cells. Annals of the New York Academy of Sciences 1031: 143-157. Conte C, Floridi A, Aisa C, et al. (2004). Gamma-Tocotrienol metabolism and antiproliferative effect in prostate cancer cells. Annals of the New York Academy of Sciences 1031: 391-394. Hasselwander O, Kramer K, Hoppe PP, et al. (2002). Effects of feeding various tocotrienol sources on plasma lipids and aortic atherosclerotic lesions in cholesterol-fed rabbits. Food Research International 35 (2-3): 245-251.
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