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Synthetic DNA nanocirclesThese nanocircles have been used successfully to rejuvenate cells and tissues and have a promise to be a therapeutically cost efficient solution to creating pharmaceutical products. The way this technology works is by elongating telomeres and thereby rejuvenating tissues. Nanocircles, according to Telomolecular, can be used as templates for polymerases to make or to extend new telomere sequences on an existing DNA or RNA molecule. Nanocircles can be used to extend the lifespan of normal cell populations, and can also be used to induce apoptosis and death in cancerous cells. Under potential biomedical and therapeutic uses for the technology are treatment of macular degeneration, treating the effects of skin aging, treating liver degeneration, and both in vitro and in vivo anti-cancer applications. In relation to telomerase enzymes that elongate telomeres, telomere-encoding nanocircles are easier to produce and to store than telomerase enzymes, according to scientists working with these issues.
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