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RiginAccording to manufacturers who use the compound in their skin anti aging creams, the compound is an anti-inflammatory agent that helps speed tissue regeneration resulting in normalization of damaged skin. After continuous use, skin should look and act younger with new strength against aging environmental damage including sun damage. Rigin is another in series of peptides used for skin anti aging. Long chain proteins used in skin anti aging cannot penetrate the epidermis because of their molecular size. But peptides can. Other popular peptides used in anti aging creams include Acetyl Hexipeptide-3 (Argireline) and Palmitoyl Pentapeptide-3 (Matrixyl). In research, it has been found that Palmitoyl Tetrapeptide-3 suppresses the body's production of interleukins, particularly IL6, the chemical messengers that trigger the body's acute inflammatory response. Under normal circumstances, very little IL6 is secreted, and its secretion is strictly controlled. However, as people age, the regulation system develops defects, and significant levels of IL6 appear in the plasma, even when there's no inflammatory stimulus. This produces high levels of inflammatory proteins in the tissues, a loss of healing potential and slower tissue regeneration. Similar to DHEA, it is suggested that Palmitoyl Tetrapeptide-3 may be able to assist in restoring cytokine equilibrium, bringing forth more youthful skin. There have also been suggestions that compound is able to stop and even reverse glycation damage that causes skin ageing. Glycation is the process by which glucose links with proteins and causes them to bind together, thus stiffening tissues. Rigin - StudiesMuch of the research on the compound has been done by French company Sederma. One such research paper is available from 1800patches: Rigin research from Sederma (opens up a new window).
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