Polysaccharides
Polysaccharides are very long-chain sugar molecules that provide nourishment for macrophages, the large white blood cells central to body's defense system.
There are some of these compounds, many of which have shown promise in anti aging research.
For example, the LBP-3 polysaccharide isolated from the Goji berry has been shown to have anti-cancer effects. In fact, there are four health beneficial polysaccharides discovered in Goji berries that have not been found in any other fruit.
In particular, the LBP polysaccharide complex unique to Goji berries has been found to be a secretagogue - a substance that stimulates the secretion of human growth hormone (HGH) by the pituitary gland, which is why many athletes use the Goji berry extract as a supplement.
The polysaccharide research in terms of antiaging is an expanding one, and many of these compounds have shown promise in this regard, including ones from mushrooms for antitumor activity.
Polysaccharides - Studies
Cao GW, Yang WG, Du P. [Observation of the effects of LAK/IL-2 therapy combining with Lycium barbarum polysaccharides in the treatment of 75 cancer patients] Zhonghua Zhong Liu Za Zhi. 1994;16:428-31. Chinese.
Gan L, Wang J, Zhang S. [Inhibition the growth of human leukemia cells by Lycium barbarum polysaccharide]. Wei Sheng Yan Jiu. 2001;30:333-5. Chinese.
Lu CX, Cheng BQ. [Radiosensitizing effects of Lycium barbarum polysaccharide for Lewis lung cancer] Zhong Xi Yi Jie He Za Zhi. 1991;11:611-2, 582. Chinese.
Zhao R, Li Q, Xiao B. [Effect of Lycium barbarum polysaccharide on the improvement of insulin resistance in NIDDM rats] Yakugaku Zasshi. 2005 Dec;125(12):981-8.
He YL, Ying Y, Xu YL, Su JF, Luo H, Wang HF. [Effects of Lycium barbarum polysaccharide on tumor microenvironment T-lymphocyte subsets and dendritic cells in H22-bearing mice] Zhong Xi Yi Jie He Xue Bao. 2005 Sep;3(5):374-7. Chinese.
Gan L, Hua Zhang S, Liang Yang X, Bi Xu H. [Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum] Int Immunopharmacol. 2004 Apr;4(4):563-9.
Anti-tumor polysaccharides from mushrooms during storage.
Mizuno M. Biofactors 2000;12(1-4):275-81.
Pleurotus mushrooms. Part II. Chemical composition, nutritional value, post-harvest physiology, preservation, and role as human food. Bano Z, Rajarathnam S. Crit Rev Food Sci Nutr 1988;27(2):87-158
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