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MolybdenumSulfite oxidase catalyzes the transformation of sulfite to sulfate, which is a reaction that is necessary for the metabolism of sulfur-containing amino acids, such as cysteine. The compound also acts as a cofactor for xanthine oxidase and aldehyde oxidase enzymes. Of these two, xanthine oxidase catalyzes the breakdown of nucleotides (precursors to DNA and RNA) to form uric acid, contributing to the antioxidant capacity of the blood. Aldehyde oxidase and xanthine oxidase catalyze hydroxylation reactions involving a number of different molecules with similar structures. Also, both play a role in the metabolism of drugs and toxins. Molybdenum - StudiesWuebbens MM, Liu MT, Rajagopalan K, Schindelin H. Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC. Structure Fold Des. 2000;8(7):709-718. Turnlund JR, Keyes WR, Peiffer GL, Chiang G. Molybdenum absorption, excretion, and retention studied with stable isotopes in young men during depletion and repletion. Am J Clin Nutr. 1995;61(5):1102-1109. (PubMed) Turnlund JR, Keyes WR, Peiffer GL. Molybdenum absorption, excretion, and retention studied with stable isotopes in young men at five intakes of dietary molybdenum. Am J Clin Nutr. 1995;62(4):790-796.
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