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ManganeseTogether, they create the compound containing superoxide dismutase (Mn-SOD), which is an enzyme typically present in mitochondria. The Mn-SOD enzyme is present in nearly all organisms living in the presence of oxygen and use it to deal with the toxic effects of oxygen. Manganese also has a role in energy production, in normal bone formation and development, as well as the synthesis of collagen, prothrombin, urea, glucosamine, chondroitin, fatty acids, and protein. The compound is toxic in excess, as are other widespread metals such as iron, nickel and copper. In 2005, a study published in the Medical Hypotheses journal suggested a possible link between manganese inhalation and central nervous system toxicity in rats. The research further hypothesized that long-term exposure to manganese in shower water puts up to 8.7 million Americans at risk for CNS neurotoxicity. This has been the reason why some anti aging experts suggest using a shower head filter that purifies the water from such compounds. Manganese - StudiesNeurotoxicity of inhaled manganese: Public health danger in the shower?. Medical Hypotheses, Volume 65, Issue 3, Pages 607-616 R. Elsner, J. Spangler. Commentary on possible manganese toxicity from showering: Response to critique. Spangler JG, Elsner R. Medical Hypotheses 2006 (Vol. 66, Issue 6, Pages 1231-1233). Neurotoxicity of inhaled manganese: A reanalysis of human exposure arising from showering, 19 September 2005 Dorman DC, Wong BA. Medical Hypotheses 2006 (Vol. 66, Issue 1, Pages 199-200). Manganese in the shower: Mere speculation over an invalidated public health danger, 14 September 2005
Aschner M. Medical Hypotheses 2006 (Vol. 66, Issue 1, Pages 200-201).
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