Mahonia Grape Extract

Mahonia grape extract contains isoquinoline alkaloid constituents including berberine, berbamine and oxyacanthine, which have been associated with antibacterial and anti-inflammatory effects.

Many of the positive effects found in studies for the herb are associated with berberine, which has been found to exhibit anticonvulsant, sedative, hypotensive, antifibrillatory, bile-stimulating and anti-inflammatory effects. In low doses it also is a cardiac and respiratory stimulant.

On their own in researh, berberine extracts have demonstrated significant antimicrobial activity against a variety of organisms including bacteria, viruses, fungi, protozoans, helminths, and chlamydia.

The herb and it's active ingredients have been studied and may have a role in prevention or treatment of acne, chronic candidiasis, conjunctivitis/blepharitis, chronic constipation, colds, flu, eczema, gallbladder conditions, protozoal or bacterial Infections, dysentery, malaria, parasites, poor digestion, psoriasis and urinary tract infections.

Mahonia Grape Extract - Studies

Gieler U, von der Weth A, Heger M. Mahonia aquifolium- a new type of topical treatment for psoriasis. J Dermatol Treatment 1995;6:31-4.

Wiesenauer M, Lydtke R. Mahonia aquifolium in patients with Psoriasis vulgaris; an intraindividual study. Phytomedicine 1996;3(3):231-5.

Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol Cancer Ther. 2006 Feb;5(2):296-308.

Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. J Med Food. 2005 Winter;8(4):454-61.

Cardiovascular actions of berberine. Cardiovasc Drug Rev. 2001 Fall;19(3):234-44.


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