Lipase

Lipase is a digestive enzyme that is responsible for breaking down fats, in particular triglycerides, digested from dietary sources.

In the body, the enzyme is produced in the pancreas but is also produced in the mouth and stomach.

Other pancreatic enzymes include amylase, which breaks down amylose into its sugar building blocks, and protease, which breaks down protein.

Poor eating habits, which may include inadequate chewing and eating, can result in inadequate enzyme production and hence malabsorption of food.

And this is effect is increased with aging, as aging is associated with decreased hydrochloric acid production as well as of a general decline in digestive enzyme secretion.

Lipase - Studies

Berkow R, ed. The Merck Manual of Medical Information. Home Ed. Whitehouse Station, NJ: Merck Research Laboratories; 1997.

Carroccio A, Iacono G, Montalto G, et al. Pancreatic enzyme therapy in childhood celiac disease. A double-blind prospective randomized study. Dig Dis Sci. 1995;40(12):2555-2560.

Heck AM; Yanovski JA; Calis KA. Orlistat, a new lipase inhibitor for the management of obesity. Pharmacother. 2000 Mar;20(3):270-279.

Physicians' Desk Reference. 55th ed. Montvale, NJ: Medical Economics Company, Inc.; 2001.

Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease. 9th ed. Philadelphia, Pa.: Lea and Febiger; 1999

Suarez F, Levitt MD, Adshead J, Barkin JS. Pancreatic supplements reduce symptomatic response of healthy subjects to a high fat meal. Dig Dis Sci. 1999;44(7):1317-1321.

Yanovski SZ, Yanovski JA. Obesity. N Engl J Med. 2002;346:591-602.


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