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Inositol

Inositol is a simple carbohydrate and essential to human health.

The compound is utilized by the body for a variety of metabolic processes, it is used by the body to form cell membranes, and it allows for the proper functioning of cells.

More specifically, it is involved in phospholipids which function as cellular mediators of signal transduction, metabolic regulation, and growth. It also acts as a lipotropic which converts fats into other useful products

From anti aging perspective, research has suggested that the compound assists enzymatic activity, assists in maintaining healthy cholesterol levels, it aids in the control of estrogen levels, normal functioning of brain cells, the eyes and the intestines.

Humans can make inositol in the body, but the compound is also available as a dietary supplement.

Inositol - Studies

The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial.Br J Dermatol. 2004 May;150(5):966-9.

Single photon emission computed tomography (SPECT) in obsessive-compulsive disorder before and after treatment with inositol. Metab Brain Dis. 2004 Jun;19(1-2):125-34

Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2003 Nov-Dec;7(6):151-9.

Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. Ben Gurion University of the Negev, Beer-Sheba, Israel. J Clin Psychopharmacol. 2001 Jun;21(3):335-9.

Controlled trials of inositol in psychiatry. Eur Neuropsychopharmacol. 1997 May;7(2):147-55. Levine J. Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheva, Israel.

Effects of d-chiro- inositol in lean women with the polycystic ovary syndrome. Endocr Pract. 2002 Nov-Dec;8(6):417-23.

Kitamura H, Yamauchi A, Sugiura T, et al. Inhibition of myo-inositol transport causes acute renal failure with selective medullary injury in the rat. Kidney Int 1998;53:146-153.

Barkai A, Dunner D, Gross H, et al. Reduced myo-inositol levels in cerebrospinal fluid from patients with affective disorder. Biol Psychiatry 1978;13:65-72.

Levine J. Controlled trials of inositol in psychiatry. Eur. Neuro. Psycho. pharmocol. 1997;7:147-155.

Cohen H, Kotler M, Kaplan Z, et al. Inositol has behavioral effects with adaptation after chronic administration. J Neural Transm 1997;104:299-305.

Levine J, Barak Y, Gonzalves M, et al. Double-blind, controlled trial of inositol treatment of depression. Am J Psychiatry 1995;152:792-794.

Levine J, Barak Y, Kofman O, et al. Follow-up and relapse of an inositol study of depression. Isr J Psychiatry Relat Sci 1995;32:14-21.

Tarnow P, Cassuto J, Jonsson A, et al. Postoperative analgesia by D-myo-inositol-1,2,6-triphosphate in patients undergoing cholecystectomy. Anesth Analg 1998;86:107-110.

Phaneuf S, Europe-Finner G, Carrasco M, et al. Oxytocin signalling in human myometrium. Adv Exp Med Biol 1995;395:453-467.

Greene N, Copp A. Inositol prevents folate-resistant neural tube defects in the mouse. Nat Med 1997;3:60-66.

Levine J, Barak Y, Gonzalves M, et al. Double-blind, controlled trial of inositol treatment of depression. Am J Psychiatry 1995;152:792-4.

Levine J, Barak Y, Kofman O, Belmaker RH. Follow-up and relapse analysis of an inositol study of depression. Isr J Psychiatry Relat Sci 1995;32:14-21.

Benjamin J, Levine J, Fux M, et al. Double-blind, placebo-controlled, crossover trial of inositol treatment for panic disorder. Am J Psychiatry 1995;152:1084-6.

Fux M, Levine J, Aviv A, Belmaker RH. Inositol treatment of obsessive-compulsive disorder. Am J Psychiatry 1996;153:1219-21.


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