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Epigallocatechin-3-Gallate
Epigallocatechin-3-Gallate (EGCG), thought to be the active ingredient behind green tea's positive effects on human health, has shown great antioxidant potential.The compound has also anti-inflammatory potential (it's been shown to decrease the production of inflammatory prostaglandin E2). EGCG is the most abundant catechin in green tea (Camellia sinensis), and has shown cancer preventive activity in animal models, which has lead to a surge in research on not only green tea, but also EGCG. It should be noted that in addition to EGCG, the other flavonoids that are active in green tea include catechin, epicatechin, epicatechin gallate, and proanthocyanidins. Of the studies that have concentrated on the EGCG compound, there are several findings that are interesting from anti aging viewpoint. For example, studies suggest that EGCG inhibits the growth of breast cancer cells, both in live animals and test tubes. Also, Phenol sulsotransferases are involved in cancer growth, and EGCG was shown to inhibit this activity in a human colon cancer call line. Similarly, EGCG has shown potency in preventing and suppressing lung cancer, pancreatic cancer, prostate cancer, skin cancer, and stomach cancer. In terms of antioxidant potency, researchers at the University of Kansas feel that EGCG is at least 100 times more effective than vitamin C and 25 times better than vitamin E as an antioxidant, and has twice the antioxidant potency of resveratrol, found in red wine. Epigallocatechin-3-Gallate - StudiesAnderson JW, Diwadkar VA, Bridges SR. Selective effects of different antioxidants on oxidation of lipoproteins from rats. Proc Soc Exp Biol Med. 1998 Sep;218(4):376-81. Benzie IF, Szeto YT, Strain JJ, Tomlinson B. Consumption of green tea causes rapid increase in plasma antioxidant power in humans. Nutr Cancer. 1999;34(1):83-7. 3. 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