DMG
DMG (dimethylglycine) acts as a building block for the synthesis of important substances such as choline, SAM-e, the amino acid methionine, and several hormones.The compound is found in low levels in foods such as cereal grains, liver, and beans. Humans also produce the compound in small amounts. DMG is a methyl donor, which is important from anti aging perspective. A methyl donor is a substance that can transfer a methyl group to another substance. Many important biochemical processes rely on methylation, including the metabolism of lipids and DNA. In research, it has been suggested that adequate methylation of DNA can prevent the expression of harmful genes, such as cancer genes. Also, it is likely that our ability to methylate declines with age, contributing to the aging process, and therefore supplementation could be beneficial. The research in this area, however, is ongoing. DMG - StudiesDimethylglycine supplementation does not affect plasma homocysteine concentrations in pre-dialysis chronic renal failure patients. Clin Biochem. 2004 Nov;37(11):974-6. The effect of short-term dimethylglycine (DMG) treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial. J Pediatr. 2003 Jan;142(1):62-6.
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