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Chasteberry ExtractIn studies, it has been suggested that the extract keeps prolactin secretion in check, which may benefit some women with PMS. It is worth noting that some of the newer research on the extract indicates that certain compounds in the extract may have activity similar to the brain chemical dopamine, which has been offered as the source of the extract's prolactin-suppressive action. Some of the associated alternative medical uses of the extract include a weak form of hormone replacement therapy, but much research should be done in this regard to consider it as an viable modern day alternative. Chasteberry Extract - StudiesA Vitex agnus-castus - chaste berry - extract inhibits cell growth and induces apoptosis in prostate epithelial cell lines.Planta Med. 2005 Oct;71(10):910-6. Institute of Pharmaceutical Biology, University of Basel, Schonbeinstrasse Basel, Switzerland. Chasteberry tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine. 2003 May;10(4):348-57. Fluoxetine versus Vitex agnus castus extract (chaste berry ) in the treatment of premenstrual dysphoric disorder. Hum Psychopharmacol. 2003 Apr;18(3):191-5. Evidence for estrogen receptor beta-selective activity of Vitex agnus-castus (chaste berry) and isolated flavones. Planta Med. 2003 Oct;69(10):945-7. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine. 2003 May;10(4):348-57. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 2001 May;49(5):2472-9 Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus (chaste berry) extract: results of a placebo-controlled double-blind study. Breast. 1999 Aug;8(4):175-81.
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