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CapsaicinThe study that suggested such behavior was done by Nottingham University in the UK. According to that research, molecules from the vanilloid family, to which capsaicin belongs, are able to trigger cancer cell death by attacking the cancer cell's mitochondria, whose biochemistry is very different from normal cells' mitochondria. The testings were performed in cultures of human lung cancer and pancreatic cancer. In large amounts, however, capsaicin is lethal to humans. Capsaicin - StudiesPurkiss, John R., et al. "Capsaicin stimulates release of Substance P from Dorsal Root Ganglion Via Two Distinct Mechanisms." Biochemical Societal Transactions. Vol 25, No. 3. 1997. Tominaga, Makoto., et al. "The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli." Neuron, Vol 21. 531-543. Cell Press. 1998. Henkin R (1991) '"Cooling the burn from hot peppers" JAMA 266(19):2766. Nasrawi CW, Pangborn RM (1990) "Temporal effectiveness of mouth-rinsing on capsaicin mouth-burn" Physiol Behav 47(4):617-23. Jin-Taek Hwanga, In-Ja Parkb, Jang-In Shinb, Yun Kyoung Leeb, Seong Kyu Leec, Haing Woon Baikc, Joohun Haa and Ock Jin Parkb. "Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase" Biochemical and Biophysical Research Communications Volume 338, Issue 2 , 16 December 2005, Pages 694-699.
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