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BioflavonoidsHigher levels of C vitamin and glutathione mean better protection of DNA and cell proteins against free radical damage. Higher levels of glutathione also mean better recycling of other antioxidant compounds, including estrogens, to their reduced (antioxidant) form so that these substances do not produce damage. In studies, flavonoids have been linked to reduced cardiovascular disease, cancer and osteoporosis, and many other health benefits as a result of their antioxidant, antibacterial,antiviral, anti-inflammatory, anti-allergenic properties. Several thousand flavonoids have been identified,which provide much of the flavor and color in fruits and vegetables, and also berries and flowers. Much of the research on these compounds has concentrated on citrus bioflavonoids, found in citrus fruits such as lemon, orange, tangerine, and grapefruit. Bioflavonoids - StudiesHesperidin, a citrus bioflavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice. J Nutr. 2003 Jun;133(6):1892-7. Biological properties of citrus bioflavonoids pertaining to cancer and inflammation. Curr Med Chem. 2001 Feb;8(2):135-53.Manthey JA, Grohmann K, Guthrie N. US Citrus and Subtropical Products Laboratory, USDA, ARS, SAA, Winter Haven, FL Antiproliferative activities of citrus bioflavonoids against six human cancer cell lines. J Agric Food Chem. 2002 Oct 9;50(21):5837-43. Manthey JA, Guthrie N. U.S. Citrus and Subtropical Products Laboratory, South Atlantic Area, Agricultural Research Service, U.S. Department of Agriculture, Winter Haven, Florida
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