ATP
ATP (Adenosine Triphosphate) is used in anti aging regimens to increase physical energy.
This is a compound that provides virtually all the energy needed by your body to function properly. In normal conditions at rest, our bodies are able to produce all the ATP we need.
However, it has been suggested that due to high intensity exercise and various diseases, ATP cannot be replaced fast enough by the body, which is why some use ATP supplements.
In addition to supplementing their diet for optimal ATP levels with ATP, other products used by those under conditions that require additional supplementation include, for example CoQ10.
It has been suggested that ATP supplements have some beneficial uses when on a moderate strength and cardiovascular training program for anti aging purposes.
ATP - Studies
McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.
Agteresch HJ, Rietveld T, Kerkhofs LG, et al. Beneficial effects of adenosine triphosphate on nutritional status in advanced lung cancer patients: a randomized clinical trial. J Clin Oncol 2002;20:371-8.
Sherlock CH, Corey L. Adenosine monophosphate for the treatment of varicella zoster infections: a large dose of caution. JAMA 1985;253:1444-5.
Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.
Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.
Jatoi A, Loprinzi CL. Adenosine triphosphate: does it help cancer patients "get bigger and stronger"? J Clin Oncol 2002;20:362-3.
Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.
Sklar SH, Blue WT, Alexander EJ, Bodian CA. Herpes zoster. The treatment and prevention of neuralgia with adenosine monophosphate. JAMA 1985;253:1427-30.
Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.
Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.
Leij-Halfwerk S, Agteresch HJ, Sijens PE, Dagnelie PC. Adenosine triphosphate infusion increases liver energy status in advanced lung cancer patients: an in vivo 31P magnetic resonance spectroscopy study. Hepatology 2002;35:421-4.
Kichenin K, Seman M. Chronic oral administration of ATP modulates nucleoside transport and purine metabolism in rats. J Pharmacol Exp Ther 2000;294:126-33.
Sklar SH, Buimovici-Klein E. Adenosine in the treatment of recurrent herpes labialis. Oral Surg Oral Med Oral Pathol 1979;48:416-7.
Williams M, Jarvis MF. Purinergic and pyrimidinergic receptors as potential drug targets. Biochem Pharmacol 2000;59:1173-85.
Sklar SH, Alexander EJ, Blue WT, Bodian CA. Herpes zoster: adenosine monophosphate for the prevention of post-neuralgia. JAMA 1985;254:912.
Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50.
Aqel RA, Zoghbi GJ, Trimm JR, et al. Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease. Am J Cardiol 2004;93:343-6.
Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76.
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